Anti-fungal
Medication Shows Potential As A New Cancer Treatment
A commonly used antifungal treatment, has joined a ranks of drugs that are likely to be suitable for use in treating cancer. This is according to research from the project Repurposing Drugs in Oncology (ReDO) published in ecancermedicalscience.
The Redo Project is an international collaborator of anticancer researchers dedicated to promoting common drugs that may be an untapped source of new therapies for cancer.
In partnership with ecancer, the Redo project publishes a series of papers on drugs that have sufficient clinical evidence to take to clinical trials.
Itraconazole is a drug used to treat various yeast infections, including skin and nail infections. This drug also has a lot of potential as a new cancer treatment, according to the ReDo project.
"Itraconazole shows potential in a number of areas with high patient needs, particularly in non-small cell lung cancer and possibly in some rare cases of malignancy," said Pan Pantziarka, Ph.D., a member of the ReDO project and Anticancer Fund. "There are a number of ongoing clinical trials for a variety of different cancers and is an exciting beginning."
According Pantziarka, itraconazole, a generic agent whose price is relatively cheap, shows some evidence of success in metastatic prostate cancer. This makes itraconazole attractive, given the high costs associated with the treatment of prostate cancer, such as Abiraterone.
It can make itraconazole an attractive cancer treatment, especially in low- and middle-income countries.
However, there are some obstacles to be overcome before this antifungal drug can reach the anticancer market.
"Our goal in collecting data on drugs used for other purposes is to do more than just bring attention to the medical community," says study author Lydie Meheus, Ph.D. from Anticancer Fund, Belgium.
"It's clear that the pharmaceutical industry will not be interested in dealing with commercially disregarded drugs," says Meheus, as reported by ecancer
According to the ReDO project leader, however, drugs used for other purposes for anticancer, such as antifungals and painkillers may represent the future of cancer drug research.
The researchers hope that increased awareness will bring the drugs out of the medicine cabinet for cancer treatment.
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